Agstafa raion wis creatit on 24 Januar 1939 as an independent admeenistrative unit oot o lairger Qazakh region o Azerbaijan. On 4 December 1959, the status o the raion wis abolished an it wis incorporatit intae Qazakh Rayon. Then on 14 Aprile 1990 bi the decree o the Cooncil o Deputees o Azerbaijan SSR, it wis split frae Qazakh raion an wis again re-established as a separate raion. The regional center o the raion is its caipital Ağstafa. The raion is locatit in the northwastren pairt o the kintra, atween Qabirri basin an Lesser Caucasus muntain range, an Ganja-Qazakh lawlands an Ceyrançöl highlands. It is sandwiched bi Qazakh raion in the wast an Tovuz raion in east, an borders Armenie on the soothren frontier an Georgie on the north. The aurie o the raion is 1,503.7 km2. Thare are 36 veelages in the raion. Thare are 39 seicontary schuils, lyceum, muisical schuil, 2 museums, 38 cultural clubs, State Airts Gallery, 49 libraries, 3 ceety an 10 veelage hospitals functionin in the raion. Ganja, Qazakh an Qarayazi lawlands mak up the maist o the raion's aurie, whilst its soothwastren an northeastren pairts comprise lesser muntain steids.
The aurie's name comes frae the name o the Oghuz Turks which include mainly the population o Azerbaijan, Turkey an Turkmenistan. Ağstafa is a merger o twa wirds: Oğuz + tayfa(Oghuz + tribe). Housomeivver, some fowk argue that it is a merger o the ither twa wirds which are: Oğuz + təpə(Oghuz + hill).