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Dolly (sheep)

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Dolly
Dolly's taxidermied remains
Ither name(s)6LLS (code name)
SpeciesDomestic sheep, Finn-Dorset
SexFemale
Born5 July 1996
Roslin Institute, Edinburgh, Scotland
Dee'd14 February 2003 (aged 6)
Roslin Institute, Edinburgh, Scotland
Restin placeNational Museum of Scotland (remains on display).
Naition fraeUnited Kingdom (Great Britain)
Kent forFirst mammal cloned from an adult somatic cell
AffspringSix lambs (Bonnie; twins Sally and Rosie; triplets Lucy, Darcy and Cotton)
Named efterDolly Parton[1]
Cause o daith
Lung disease and severe arthritis

Dolly (5 Julie 1996 – 14 Februar 2003) wis a female domestic sheep, an the first mammal cloned frae an adult somatic cell, uisin the process o nuclear transfer.[2][3] She wis cloned bi Ian Wilmut, Keith Campbell an colleagues at the Roslin Institute, pairt o the Varsity o Edinburgh, Scotland, an the biotechnology company PPL Therapeutics, based near Edinburgh. The fundin for Dolly's clonin wis providit bi PPL Therapeutics an the UK's Meenistry o Agricultur.[4] She wis born on 5 Julie 1996 an died frae a progressive lung disease five month afore her seivent birthday.[5] She haes been cried "the warld's maist famous sheep" bi soorces includin BBC News an Scientific American.[6][7]

The cell uised as the donor for the clonin o Dolly wis taken frae a mammary gland, an the production o a healthy clone tharefore proved that a cell taken frae a speceefic pairt o the bouk could recreate a whole individual. On Dolly's name, Wilmut stated "Dolly is derived frae a mammary gland cell an we couldn't think o a mair impressive pair o glands than Dolly Parton's".[1]

References

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  1. a b "1997: Dolly the sheep is cloned". BBC News. 22 Februar 1997.
  2. McLaren A (2000). "Cloning: pathways to a pluripotent future". Science. 288 (5472): 1775–80. doi:10.1126/science.288.5472.1775. PMID 10877698.
  3. Wilmut I; Schnieke AE; McWhir J; Kind AJ; et al. (1997). "Viable offspring derived from fetal and adult mammalian cells". Nature. 385 (6619): 810–3. Bibcode:1997Natur.385..810W. doi:10.1038/385810a0. PMID 9039911.
  4. Edwards, J. (1999). "Why dolly matters: Kinship, culture and cloning". Ethnos. 64 (3–4): 301–324. doi:10.1080/00141844.1999.9981606.
  5. "Dolly the sheep clone dies young". BBC News. 14 February 2003
  6. "Is Dolly old before her time?". BBC News. London. 27 Mey 1999. Retrieved 4 October 2009.
  7. Lehrman, Sally (Julie 2008). "No More Cloning Around". Scientific American. Retrieved 21 September 2008.