Template:PBB/5741

Parathyroid hormone
PDB renderin based on 1bwx.
Available structurs PDB Ortholog search: PDBe, RCSB Leet o PDB id codes 1BWX, 1ET1, 1ET2, 1FVY, 1HPH, 1HPY, 1HTH, 1ZWA, 1ZWB, 1ZWD, 1ZWE, 1ZWF, 1ZWG, 2L1X, 3C4M
Identifiers
Seembols	PTH ; PTH1
Freemit IDs	OMIM: 168450 MGI: 97799 HomoloGene: 266 GeneCards: PTH Gene
Gene ontology Molecular function • RNA polymerase II distal enhancer sequence-specific DNA bindin transcription factor activity • hormone activity • parathyroid hormone receptor binding • type 1 parathyroid hormone receptor binding • peptide hormone receptor binding Cellular component • extracellular region • extracellular space • intracellular Biological process • negative regulation o transcription frae RNA polymerase II promoter • skeletal seestem development • cellular calcium ion homeostasis • G-protein coupled receptor signalin pathway • adenylate cyclase-activatin G-protein coupled receptor signalin pathway • Rho protein signal transduction • cell-cell signaling • hormone-mediatit apoptotic signalin pathway • positive regulation o signal transduction • response tae lead ion • regulation o gene expression • positive regulation o bane mineralization • positive regulation o cAMP biosynthetic process • response tae vitamin D • cellular macromolecule biosynthetic process • response tae drog • bane resorption • response tae ethanol • positive regulation o glycogen biosynthetic process • positive regulation o transcription frae RNA polymerase II promoter • cAMP metabolic process • positive regulation o glucose import • response tae cadmium ion • response tae parathyroid hormone • response tae fibroblast growth factor Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Moose
Entrez	5741	19226
Ensembl	ENSG00000152266	ENSMUSG00000059077
UniProt	P01270	n/a
RefSeq (mRNA)	NM_000315	NM_020623
RefSeq (protein)	NP_000306	NP_065648
Location (UCSC)	Chr 11: 13.49 – 13.5 Mb	Chr 7: 113.39 – 113.39 Mb
PubMed search	[1]	[2]