Oliver Smithies
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Oliver Smithies | |
---|---|
Smithies offeecial Gold Medal of the Archaeological Institute of America portrait (2009) | |
Born | 23 Juin 1925 Halifax, Wast Yorkshire, Ingland |
Died | 10 Januar 2017 Chapel Hill, North Carolina, US | (aged 91)
Naitionality | Unitit Kinrick, Unitit States |
Alma mater | Varsity o Oxford (BA , PhD) |
Kent for | |
Awairds |
|
Scientific career | |
Fields | |
Institutions | |
Thesis | Physico-chemical properties of solutions of proteins (1951) |
Oliver Smithies (23 Juin 1925 – 10 Januar 2017) wis a Breetish-born American geneticist an Nobel laureate,[2] creditit wi the introduction o starch as a medium for gel electrophoresis in 1955,[3] an the simultaneous discovery, wi Mario Capecchi an Martin Evans, o the technique o homologous recombination o transgenic DNA wi genomic DNA, a much mair reliable method o alterin ainimal genomes than previously uised, an the technique behind gene tairgetin an knockoot mice.[4][5][6]
References[eedit | eedit soorce]
- ↑ "Fellows of the Royal Society". London: Royal Society. Archived frae the original on 16 Mairch 2015.
- ↑ "The Nobel Prize in Physiology or Medicine 2007". The Nobel Foundation. Retrieved 8 October 2007.
- ↑ Smithies, Oliver (December 1955). "Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults". The Biochemical Journal. 61 (4): 629–641. ISSN 0264-6021. PMC 1215845. PMID 13276348.
- ↑ Smithies, Oliver (2001). "Forty years with homologous recombination". Nature Medicine. 7 (10): 1083–1086. doi:10.1038/nm1001-1083. ISSN 1078-8956.
- ↑ Williams, R. (2011). "Oliver Smithies: Born Inventor". Circulation Research. 108 (6): 650–652. doi:10.1161/RES.0b013e318216f105. ISSN 0009-7330.
- ↑ Gitschier, Jane (2015). "The Whole of a Scientific Career: An Interview with Oliver Smithies". PLOS Genetics. 11 (5): e1005224. doi:10.1371/journal.pgen.1005224. ISSN 1553-7404. PMC 4447374. PMID 26020970.
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