Methadone

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Methadone
Methadone.svg
Methadone3DanJ.gif
Clinical data
Tred namesDolophine
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa682134
Pregnancy
category
  • AU: C
  • US: C (Risk nae ruled oot)
Routes o
admeenistration
Oral, intravenous, insufflation, sublingual, rectal
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability41-99% (oral)[1]
MetabolismHepatic (CYP3A4, CYP2B6 an CYP2D6-mediatit)[1][2]
Biological hauf-life7-65 oors[2]
ExcretionUrine, faeces[2]
Identifiers
CAS Nummer
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard100.000.907
Chemical and physical data
FormulaC21H27NO
Molar mass309.445 g/mol
3D model (Jmol)
  (verify)

Methadone (an aa kent as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon an mony ither names) is a synthetic opioid.

References[eedit | eedit soorce]

  1. 1.0 1.1 1.2 Fredheim, OM; Moksnes, K; Borchgrevink, PC; Kaasa, S; Dale, O (August 2008). "Clinical pharmacology of methadone for pain". Acta Anaesthesiologica Scandinavica. 52 (7): 879–89. doi:10.1111/j.1399-6576.2008.01597.x. PMID 18331375.
  2. 2.0 2.1 2.2 Brown, R; Kraus, C; Fleming, M; Reddy, S (November 2004). "Methadone: applied pharmacology and use as adjunctive treatment in chronic pain" (PDF). Postgraduate Medical Journal. 80 (949): 654–9. doi:10.1136/pgmj.2004.022988. PMC 1743125. PMID 15537850.