Integrin

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Integrin alphavbeta3 extracellular domeens
PDB 1jv2 EBI.jpg
Structur o the extracellular segment o integrin alpha Vbeta3.[1]
Identifiers
Seembol Integrin_alphaVbeta3
Pfam PF08441
Pfam clan CL0159
InterPro IPR013649
SCOP 1jv2
SUPERFAMILY 1jv2
OPM superfamily 176
OPM protein 2knc
Integrin alpha cytoplasmic region
PDB 1dpk EBI.jpg
Structure of chaperone protein PAPD.[2]
Identifiers
Seembol Integrin_alpha
Pfam PF00357
InterPro IPR000413
PROSITE PDOC00215
SCOP 1dpk
SUPERFAMILY 1dpk
Integrin, beta cheen
Integrinalpha.png
Identifiers
Seembol Integrin_beta
Pfam PF00362
InterPro IPR002369
SMART SM00187
PROSITE PDOC00216
SCOP 1jv2
SUPERFAMILY 1jv2
Integrin beta 7 cytoplasmic domain: complex with filamin
PDB 2brq EBI.jpg
creestal structur o the filamin a repeat 21 complexed wi the integrin beta7 cytoplasmic tail peptide
Identifiers
Seembol Integrin_b_cyt
Pfam PF08725
InterPro IPR014836
SCOP 1m8O
SUPERFAMILY 1m8O

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

References[eedit | eedit soorce]

  1. Xiong JP, Stehle T, Diefenbach B, Zhang R, Dunker R, Scott DL, Joachimiak A, Goodman SL, Arnaout MA (October 2001). "Crystal structure of the extracellular segment of integrin alpha Vbeta3". Science. 294 (5541): 339–45. doi:10.1126/science.1064535. PMC 2885948Freely accessible. PMID 11546839. 
  2. Sauer FG, Fütterer K, Pinkner JS, Dodson KW, Hultgren SJ, Waksman G (August 1999). "Structural basis of chaperone function and pilus biogenesis". Science. 285 (5430): 1058–61. doi:10.1126/science.285.5430.1058. PMID 10446050.