Crohn's disease

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Crohn's disease
SynonymsCrohn syndrome, regional enteritis
Patterns of Crohn's Disease.svg
The three maist common steids o intestinal involvement in Crohn's disease are
SpecialtyGastroenterology
SymptomsAbdominal pain, diarrhoea (mey be bluidy), fiver, wecht loss[1]
ComplicationsAnemia, skin rashes, arthritis, bouel cancer[1]
Uisual onset20 tae 30[2]
DurationLang term[1]
Risk factorsTobacco smeukin[3]
Diagnostic methodBiopsy, medical eemagin[1]
Seemilar condeetionsIrritable bouel syndrome, celiac disease, Behçet's disease, nonsteroidal anti-inflammatory drog enteropathy, intestinal tuberculosis[1][4]
MedicationCorticosteroids, methotrexate[1]
PrognosisSlichtly reduced life expectancy[1]
Frequency3.2 per 1,000 (developit warld)[5]
Daiths47,400 wi ulcerative colitis (2015)[6]

Crohn's disease is a teep o inflammatory bouel disease (IBD) that mey affect ony part o the gastrointestinal tract frae mooth tae anus.[2] Signs an symptoms eften include abdominal pyne, diarrhoea (that mey be bluidy if inflammation is severe), fiver, an wecht loss.[1][2]

References[eedit | eedit soorce]

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Baumgart DC, Sandborn WJ; Sandborn (2012). "Crohn's disease". The Lancet. 380 (9853): 1590–605. doi:10.1016/S0140-6736(12)60026-9. PMID 22914295. Open Access logo PLoS transparent.svg
  2. 2.0 2.1 2.2 "Crohn's Disease". National Digestive Diseases Information Clearinghouse (NDDIC). July 10, 2013. Archived frae the oreeginal on June 9, 2014. Retrieved June 12, 2014. 
  3. Cosnes J (2004). "Tobacco and IBD: Relevance in the understanding of disease mechanisms and clinical practice". Best Practice & Research Clinical Gastroenterology. 18 (3): 481–96. doi:10.1016/j.bpg.2003.12.003. PMID 15157822. 
  4. "Inflammatory Bowel Disease" (PDF). World Gastroenterology Organization. August 2015. Archived (PDF) frae the oreeginal on March 14, 2016. Retrieved March 13, 2016. 
  5. Molodecky, NA; Soon, IS; Rabi, DM; Ghali, WA; Ferris, M; Chernoff, G; Benchimol, EI; Panaccione, R; Ghosh, S; Barkema, HW; Kaplan, GG (Jan 2012). "Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review". Gastroenterology. 142 (1): 46–54.e42; quiz e30. doi:10.1053/j.gastro.2011.10.001. PMID 22001864. 
  6. GBD 2015 Mortality and Causes of Death, Collaborators. (October 8, 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/S0140-6736(16)31012-1. PMID 27733281.