Chagas disease

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Chagas disease
SynonymsAmerican trypanosomiasis
Trypanosoma cruzi crithidia.jpeg
Photomicrograph o Giemsa-stained Trypanosoma cruzi
SpecialtyInfectious disease
SymptomsFever, large lymph nodes, headache[1]
CausesTrypanosoma cruzi spread bi kissin bugs[1]
Diagnostic methodFindin the parasite or antibodies in the bluid[2]
MedicationBenznidazole, nifurtimox[1]
Frequency6.6 million (2015)[3]
Daiths8,000 (2015)[4]

Chagas disease, an aa kent as American trypanosomiasis, is a tropical parasitic disease caused bi the protozoan Trypanosoma cruzi.[1] It is spread maistly bi insects kent as Triatominae or kissin bugs.[1] The seemptoms chynge ower the coorse o the infection. In the early stage, seemptoms are teepically either nae present or mild, an mey include fever, swalt lymph nodes, heidaches, or local swellin at the steid o the bite.[1] Efter 8–12 weeks, individuals enter the chronic phase o disease an in 60–70% it niver produces further seemptoms.[5][2] The ither 30 tae 40% o fowk develop further seemptoms 10 tae 30 years efter the ineetial infection,[2] includin enlairgement o the ventricles o the hert in 20 tae 30%, leadin tae hert failyie.[1] An enlairged esophagus or an enlairged colon mey an aa occur in 10% o fowk.[1]

References[eedit | eedit soorce]

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 "Chagas disease (American trypanosomiasis) Fact sheet N°340". World Health Organization. March 2013. Retrieved 23 February 2014.
  2. 2.0 2.1 2.2 Rassi A Jr, Rassi A, Marcondes de Rezende J (June 2012). "American trypanosomiasis (Chagas disease)". Infectious disease clinics of North America. 26 (2): 275–91. doi:10.1016/j.idc.2012.03.002. PMID 22632639.
  3. GBD 2015 Disease and Injury Incidence and Prevalence, Collaborators. (8 October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet (London, England). 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
  4. GBD 2015 Mortality and Causes of Death, Collaborators. (8 October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet (London, England). 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMID 27733281.
  5. Rassi A, Rassi A, Marin-Neto JA (April 2010). "Chagas disease". Lancet. 375 (9723): 1388–402. doi:10.1016/S0140-6736(10)60061-X. PMID 20399979.