Botulinum toxin

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Botulinum toxin A
Cartoon representation o Botulinum toxin. PDB entry 3BTA
Clinical data
Routes o
admeenistration
IM (approved), SC, intradermal, into glands
ATC code
Legal status
Legal status
Identifiers
CAS Nummer
DrugBank
ChemSpider
  • none
ECHA InfoCard100.088.372
Chemical and physical data
FormulaC6760H10447N1743O2010S32
Molar mass150 kg/mol (150,000 g/mol)
 NYesY (whit is this?)  (verify)
Bontoxilysin
Identifiers
EC nummer3.4.24.69
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structursRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Botulinum toxin (BTX) is a neurotoxic protein produced bi the bacterium Clostridium botulinum an relatit species.[1] It prevents the release o the neurotransmitter acetylcholine frae axon endins at the neuromuscular junction an thus causes flaccid paralysis. Infection wi the bacterium causes the disease botulism. The toxin is an aa uised commercially in medicine, cosmetics, an resairch.

References[eedit | eedit soorce]

  1. Montecucco C, Molgó J (June 2005). "Botulinal neurotoxins: revival of an old killer". Current Opinion in Pharmacology. 5 (3): 274–9. doi:10.1016/j.coph.2004.12.006. PMID 15907915.