Botulinum toxin

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Botulinum toxin A
Cartoon representation o Botulinum toxin. PDB entry 3BTA
Clinical data
Routes o
admeenistration
IM (approved), SC, intradermal, into glands
ATC code
Legal status
Legal status
Identifiers
CAS Nummer
DrugBank
ChemSpider
  • none
Chemical and physical data
Formula C6760H10447N1743O2010S32
Molar mass 150 kg/mol (150,000 g/mol)
 NYesY (whit is this?)  (verify)
Bontoxilysin
Identifiers
EC nummer 3.4.24.69
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structurs RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

Botulinum toxin (BTX) is a neurotoxic protein produced bi the bacterium Clostridium botulinum an relatit species.[1] It prevents the release o the neurotransmitter acetylcholine frae axon endins at the neuromuscular junction an thus causes flaccid paralysis. Infection wi the bacterium causes the disease botulism. The toxin is an aa uised commercially in medicine, cosmetics, an resairch.

References[eedit | eedit soorce]

  1. Montecucco C, Molgó J (Juin 2005). "Botulinal neurotoxins: revival of an old killer". Current Opinion in Pharmacology. 5 (3): 274–9. doi:10.1016/j.coph.2004.12.006. PMID 15907915.