Amoxicillin

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Amoxicillin
Amoxicillin.svg
Amoxicillin-3D-balls.png
Clinical data
Tred names Actimoxi, Alphamox, Amocla, Tycil, Amoxil, Trimox, amang ithers
AHFS/Drugs.com monograph
MedlinePlus a685001
Pregnancy
category
  • AU: A
  • US: B (Na risk in non-human studies)
Routes o
admeenistration
Oral, intravenous
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability 95% oral
Metabolism less than 30% biotransformed in liver
Biological hauf-life 61.3 minutes
Excretion renal
Identifiers
CAS Nummer
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.043.625
Chemical and physical data
Formula C16H19N3O5S
Molar mass 365.4 g/mol
3D model (Jmol)
  (verify)

Amoxicillin (INN), umwhile amoxycillin (BAN), an abbreviatit amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic uised tae treat bacterial infections caused bi susceptible microorganisms. It is uisually the drug o choice within the class acause it is better absorbed, follaein oral admeenistration, nor ither β-lactam antibiotics. Amoxicillin is ane o the maist common antibiotics prescribed for childer. The drug first acame available in 1972.

Amoxicillin is susceptible tae degradation bi β-lactamase-producin bacteria, which are resistant tae a broad spectrum o β-lactam antibiotics, such as penicillin. For this reason, it is eften combined wi clavulanic acid, a β-lactamase inhibitor. This increases effectiveness bi reducin its susceptibility tae β-lactamase resistance.[1]

References[eedit | eedit soorce]

  1. "Amoxicillin Susceptibility and Resistance Data" (PDF). Retrieved 20 Julie 2013.