Amoxicillin

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Amoxicillin
Systematic (IUPAC) name
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Cleenical data
Trade names Actimoxi, Alphamox, Amocla, Tycil, Amoxil, Trimox, amang ithers
AHFS/Drugs.com monograph
MedlinePlus a685001
Pregnancy cat. A (AU) B (US)
Legal status POM (UK) -only (US)
Routes Oral, intravenous
Pharmacokinetic data
Bioavailability 95% oral
Metabolism less than 30% biotransformed in liver
Hauf-life 61.3 minutes
Excretion renal
Identifiers
CAS nummer 26787-78-0 YesY
ATC code J01CA04 QG51AA03
PubChem CID 33613
DrugBank DB01060
ChemSpider 31006 YesY
UNII 9EM05410Q9 YesY
KEGG D07452 YesY
ChEBI CHEBI:2676 YesY
ChEMBL CHEMBL1082 YesY
Chemical data
Formula C16H19N3O5S 
Mol. mass 365.4 g/mol
 YesY (what is this?)  (verify)

Amoxicillin (INN), umwhile amoxycillin (BAN), an abbreviatit amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic uised tae treat bacterial infections caused bi susceptible microorganisms. It is uisually the drug o choice within the class acause it is better absorbed, follaein oral admeenistration, nor ither β-lactam antibiotics. Amoxicillin is ane o the maist common antibiotics prescribed for childer. The drug first acame available in 1972.

Amoxicillin is susceptible tae degradation bi β-lactamase-producin bacteria, which are resistant tae a broad spectrum o β-lactam antibiotics, such as penicillin. For this reason, it is eften combined wi clavulanic acid, a β-lactamase inhibitor. This increases effectiveness bi reducin its susceptibility tae β-lactamase resistance.[1]

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